Please read this whole article, but here are some highlights. The impact, however, extends to all kinds of diseases you think might be unrelated - e.g. hip dysplasia.
http://dogtorj.tripod.com/id32.html:
"...once the meat source is removed from the diet, the remaining ingredients are mostly unnatural for the pet. If we exclude the beef, poultry, fish, and lamb, the remaining calorie sources are mostly wheat, barley, corn, rice, and oats, all of which are man-raised crops that the dog and cat would never consume in the wild. ...
Allergies abated, intestinal problems cleared up, older pets became less painful and more active, and yes, even their epilepsy stopped. "Wait a second! Epileptic seizures stopped?", you may be asking. Yes, 100% of my epileptics have stopped having seizures, just like many celiac children that were placed on gluten-free diets have responded. ...
There are three food ingredients that adhere to the villi of the duodenum and induce the change that is characteristic of celiac disease known as villous atrophy. These four substances are gluten (from the grains), casein (from cow milk products), soy protein and corn gluten. ...
What is it that links these substances together? For one, they are all use as adhesives, either as non-food glues or as binders in the foods we consume. Gluten, casein, soy and even corn are all used in industry as adhesives, some even being waterproof. Put "gluten", "casein", "soy protein adhesive" or "corn adhesive" in the search engine of any computer and read the responses. Wow! They are not only used in the food industry to hold items such as oats together but they are put to use in industry to hold just about anything together. ...
It is this sticky substance that adheres to the villi of the small intestine. Whether it be from wheat, cow milk, soy, corn, or the others mentioned, it adheres to these finger-like projections of the intestine- particularly those of the duodenum and jejunum, which are vital for the absorption of nutrients- effectively reducing the amount of those essential ingredients that would be absorbed into the bloodstream. ...
How well can the intestinal tract function when it is coated with "glue"? The important thing to realize here is that this happens to some extent in everyone and every pet that eats these foods....
We have simply focused on the worst-of-the-worst- as in the celiacs, casein intolerants, and soy intolerants- in which an immune response is mounted against the glue leading to severe villous atrophy. This immune assault also generates the warning antibodies that we call "allergies" to tell you that this is process is taking place. ..."